Quarterback availability and offensive-line injuries headline the NFL’s early Week 2 roster picture, with Seattle turning to Drew Lock, Cincinnati expecting Joe Burrow to play and Minnesota monitoring Kyler Murray in concussion protocol. Wednesday’s transactions also brought several injured-reserve moves, including Arizona safety Kitan Crawford, Baltimore receiver Ja’Kobi Lane and San Francisco rookie De’Zhaun Stribling.
NFL Week 2 Injury Report: Drew Lock to Start for Seahawks, Burrow Cleared to Play
SEO Title: NFL Week 2 Injury Report: Drew Lock Starts, Joe Burrow Set to Play
SEO Description: Seattle will start Drew Lock against Arizona as Sam Darnold sits, while Joe Burrow plans to face Houston. Full Week 2 injury and roster-move roundup.
Quick facts
- Seattle quarterback Sam Darnold will miss Sunday’s game against Arizona because of a glute injury, sending Drew Lock into the starting lineup.
- Cincinnati quarterback Joe Burrow said back tightness will not keep him out against Houston on Sunday.
- Arizona safety Kitan Crawford is headed to injured reserve with a mid-ankle sprain and must miss at least four games.
- San Francisco expects rookie wideout De’Zhaun Stribling to be sidelined about 10 weeks after ankle surgery.
- Detroit ruled out tackle Blake Miller and guard Christian Mahogany for Thursday night’s road game against Buffalo.
Seattle will make the most prominent quarterback change of the week. Darnold has been ruled out for the Cardinals game, and Lock will take the snaps Sunday in Arizona.
Burrow, meanwhile, expects to remain available despite soreness in his back. The Bengals quarterback told reporters he will play when Cincinnati hosts the Texans.
Minnesota listed Murray as limited while he works through the NFL concussion protocol. The Vikings also placed running back Jordan Mason on injured reserve following surgery to repair his fractured thumb.
Arizona lost Crawford after the safety suffered a mid-ankle sprain in the Week 1 victory. The Cardinals will place him on IR, ensuring a minimum four-game absence. Arizona promoted cornerback Kalen King from its practice squad, added safety Jerrick Reed II to that squad and released practice-squad receiver Ihmir Smith-Marsette.
Atlanta put defensive lineman Da’Shawn Hand on season-ending injured reserve because of a quad injury. Guard Chris Lindstrom remained out with a concussion, while cornerback A.J. Terrell did not practice because of a shoulder issue and quarterback Tua Tagovailoa was listed with an oblique injury.
The Falcons elevated tight end Nick Muse to the active roster and signed running back Khalil Herbert and defensive end Drake Jackson to the practice squad.
Baltimore receiver Zay Flowers missed practice with a hamstring injury and is considered day to day. Receiver Ja’Kobi Lane underwent wrist surgery and went to injured reserve, leaving him out for at least four games.
The Ravens also had guard John Simpson, tackle Ronnie Stanley and outside linebacker Trey Hendrickson sidelined. Defensive tackle Nnamdi Madubuike was limited by a neck injury. Baltimore signed receiver Chris Moore and placed defensive back Amani Oruwariye on its practice squad.
Buffalo listed running back Ty Johnson, defensive lineman T.J. Sanders and safety Cole Bishop as questionable for Thursday’s matchup with Detroit. Johnson is dealing with a hamstring issue, Sanders has knee and illness concerns, and Bishop has knee and groin injuries.
Detroit will be without Miller and Mahogany against the Bills, with knee and hip injuries respectively. Cornerback D.J. Reed is questionable. The Lions promoted running back Ben VanSumeren, added defensive end Michael Heldman and cornerback Melvin Smith Jr. to the practice squad, and released practice-squad safety Tanner McCalister.
Chicago’s backfield remained limited, as Kyle Monangai worked through a hamstring problem and D’Andre Swift managed ankle and knee injuries. Right tackle Darnell Wright did not practice because of his knee, while defensive lineman Dayo Odeyingbo had limited work with a shoulder injury.
The Chargers received a full practice from guard Zion Johnson, who has a knee injury. Guard Teven Jenkins missed practice with a back problem, center Elgton Jenkins was limited by his back, and defensive tackle Maliek Collins had a limited session because of a quad injury.
Dallas did not have linebacker DeMarvion Overshown, who is nursing a hamstring injury, or safety Malik Hooker, who has a forearm issue.
Denver saw running back RJ Harvey and receiver Marvin Mims Jr. remain out of practice with hamstring and foot injuries, respectively.
Green Bay’s injury list included five limited players: guard Aaron Banks, tackle Zach Bako-Bewele, defensive tackles Javon Hargrave and Devonte Wyatt, and edge rusher Lukas Van Ness. Hargrave is managing knee and concussion concerns, while Van Ness remains in concussion protocol. The Packers promoted linebacker Jamal Hill and signed linebacker Kenneth Murray to the practice squad.
Indianapolis quarterback Anthony Richardson did not practice because of a groin injury.
Jacksonville had five limited players: running back LeQuint Allen, receiver Jakobi Meyers, receiver Brian Thomas Jr., tackle Cole Van Lanen and linebacker Foye Oluokun. Defensive end BJ Green II went to injured reserve with an elbow injury, while the Jaguars promoted linebacker Jack Kiser and signed defensive end BJ Ojulari to the practice squad.
Kansas City had full participation from Patrick Mahomes and Rashee Rice, each listed with knee injuries. Defensive tackle Chris Jones was limited with a calf issue, tackle Josh Simmons did not practice due to his back, and defensive back Chamarri Conner remained out with a knee injury.
Chiefs defensive back Mansoor Delane was a full participant with a shoulder concern, and head coach Andy Reid said Delane has a “pretty good chance” to face Indianapolis in Week 2. Defensive end R Mason Thomas and cornerback L’Jarius Sneed were full participants, while linebacker Cooper McDonald was placed on injured reserve.
Elsewhere in the secondary, a team released practice-squad cornerback Kaiir Elam after adding receiver Marquez Valdes-Scantling to its practice squad. Another club placed safety Kyle Louis on injured reserve, promoted cornerback Jaylin Simpson and signed long snapper Cal Adomitis to the practice squad.
Minnesota also had limited participation from tackle Brian O’Neill, outside linebacker Andrew Van Ginkel and linebacker Blake Cashman. The club signed running back DeeJay Dallas to the active roster and added running back Jerome Ford to its practice squad.
New England received a full session from running back TreVeyon Henderson, who is dealing with an ankle injury. Linebackers Dre’Mont Jones and Robert Spillane were limited, while cornerback Carlton Davis did not practice because of a neck injury.
New Orleans had running back Alvin Kamara back as a full participant with a knee issue. Tight end Juwan Johnson missed practice while ill, and edge rusher Cameron Jordan was limited by a hamstring injury.
One club listed receiver Omar Cooper Jr., edge rusher Joseph Ossai and safety Minkah Fitzpatrick as non-participants. Cooper has an ankle injury, Ossai is dealing with his foot and Fitzpatrick has a groin issue.
Pittsburgh limited receiver Michael Pittman with a foot injury and did not practice tackle Troy Fautanu because of his ankle. Cornerback Joey Porter Jr. had limited work in his return from a conditioning-related absence. Head coach Mike McCarthy said the team will continue evaluating how much Porter can handle.
San Francisco’s Stribling, the No. 33 overall selection in the 2026 draft, suffered his ankle injury during the Week 1 win over the Rams. The 49ers also lost tight end Jake Tonges for the season after knee surgery. San Francisco promoted receiver KhaDarel Hodge and added tight end Jack Stoll to the practice squad.
Cornerback Jacob Parrish was limited by a back issue. Linebacker Cedric Gray returned as a full participant while progressing from a concussion.
Washington signed 33-year-old guard Lucas Patrick, who appeared in six games for Cincinnati in 2025. The Commanders also placed outside linebacker Marvin Jones Jr. and linebacker Austin Keys on the practice squad.
Washington’s injury report included limited sessions for receiver Jaylin Lane, defensive tackle Daron Payne, defensive end Charles Omenihu, outside linebackers Dorance Armstrong, K’Lavon Chaisson and Odafe Oweh. Tight end Chigoziem Okonkwo and linebacker Frankie Luvu did not practice, while linebacker Jordan Magee was placed on injured reserve with a hamstring injury.
